Clinical Research Seed Grants: Review Criteria

In the initial round of funding, preference will be given to research proposals that specifically focus on scientific and clinical issues relevant to obesity, diabetes, asthma, infectious diseases at the border, cancer, the opioid epidemic, and health care delivery, including maternal child health.


Applications (up to five pages) should include a well-formulated, testable hypothesis based on strong scientific rationale that is established through inferential reasoning and/or critical review and analysis of the literature.  The review criteria includes the impact, research strategy, and the qualifications and commitment of the investigative team to the research project. Inclusion of preliminary data is encouraged.



The proposed research should impact an area of paramount importance in one of the identified diseases under the eligibility criteria described in the Call for Preliminary Proposals. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly describe the potential impacts of the proposed study in any diseases and to convey its level of significance.

  • How well does the proposed research address at least one of the focus areas listed above?
  • How well is the critical problem or question in the relevant focus area(s) addressed in the proposed research?
  • To what extent will the proposed research, whether in the short-term or long-term, lead to major advancements and significantly accelerate progress toward curing or effective management?


Research Strategy

The scientific rationale and experimental methodology should demonstrate critical understanding and in-depth analysis of the disease in question. Experimental strategies may be novel or may be based on strong rationale derived from a literature review.

  • To what degree is the proposed research supported by a sound scientific rationale?
  • How well are the hypotheses (or objectives), aims, experimental design, methods, and analyses developed and integrated into the project?
  • How innovative is the proposal?
  • To what degree are the experimental design and methodology appropriate to address the stated objectives?
  • What is the likelihood the proposed project will be completed in the stated period?
  • What is the probability the proposed project will lead to peer-reviewed extramural funding?



  • Are the investigators appropriately trained and well-suited to carry out this work?
  • Is the work proposed appropriate to the experience level of the principle investigator and his/her team?
  • Does the investigative team bring complementary and integrated expertise to the project (if applicable)?
  • How well does the PI acknowledge potential problems and address alternative approaches?


NIH Scoring System will be adapted: High Impact: 1, 2, or 3; Medium Impact: 4, 5, or 6; Low Impact: 7, 8, or 9.







Submit the proposal as a single .pdf document


  • Maximum of 5 pages, including 1 page specific aims, figures and tables (references excluded).
  • Font Size: 12 point. Font Type: Times New Roman or Arial. Spacing: Single space.
  • Page Size: No larger than 8.5 inches x 11.0 inches; Margins: At least 0.5 inch in all directions.
  • Applicant’s bio sketch: two pages, including the current, past and pending funding and latest publications (no more than 10).

PRELIMINARY grant application


Research proposals should focus on South Texas and health needs of the Hispanic population.


Please download the grant application
and procure the signatures
required for submission.

Submit completed grant applications to

Email the GIHH at